Immune Globulin-dira (i-MUNE GLOB-ue-lin - dira)

Treats problems with your immune system.

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how immune globulin-dira works. Tell your doctor if you are using estrogen, diuretics (water pill), or any medicine that may affect your kidneys.
• Talk to your doctor before you get any live virus vaccines while you are using this medicine. Some vaccines may not work as well while you are using this medicine.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart or blood vessel problems, blood clotting problems, diabetes, any type of infection, problems with your immune system, or a history of blood clots.
• This medicine may cause the following problems:
  • Bleeding problems (including hemolysis or hemolytic anemia)
  • Increased risk for blood clots
  • Kidney problems
  • Aseptic meningitis syndrome (AMS)
  • Lung problems, including transfusion-related acute lung injury (TRALI)
• This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.
• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Blue lips or fingernails, trouble breathing
• Blurred vision, headache, nervousness, pounding in the ears
• Change in how much or how often you urinate
• Chills, cough, sore throat, nausea, vomiting during the infusion
• Confusion, weakness, and muscle twitching
• Fast heartbeat, tiredness, dark urine, yellow skin or eyes
• Fever higher than 100 degrees Fahrenheit (37.7 degrees Celsius)
• Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
• Rapid weight gain, swelling in your hands, ankles, or feet
• Severe back, stomach, chest, or side pain
• Sudden or severe headache, problems with vision, speech, or walking
• Stiff neck, eye pain, sensitivity of the eye to light

If you notice these less serious side effects, talk with your doctor:

• Pain, itching, burning, redness, swelling, warmth, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088