Motixafortide (By injection)

Motixafortide (moe-tix-a-FOR-tide)

Prepares blood for a stem cell transplant as part of the treatment for multiple myeloma.

Brand Name(s):

Aphexda

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to motixafortide.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
  • A nurse or other health provider will give you this medicine.
  • Your doctor will ask you to stay for 1 hour after receiving this medicine.
  • Your doctor will give you other medicines (including allergy medicine, stomach medicine, medicine for asthma, pain medicine) 30 to 60 minutes before receiving this medicine.
  • Your doctor will give you filgrastim once a day for 4 days before receiving this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control to keep from getting pregnant during treatment and for 8 days after the last dose.
  • Do not breastfeed during treatment and for 8 days after the last dose.
  • Tell your doctor if you have blood or bone marrow problems (including leukemia).
  • This medicine may cause injection site reactions.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
  • Pain, itching, burning, swelling, or a lump under your skin where the shot is given
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice these less serious side effects, talk with your doctor:

  • Back pain
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/6/2024

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