Meloxicam (mel-OX-i-kam)

Treats moderate to severe pain.

Brand Name(s):

Anjeso

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.
• Drink extra fluids so you will urinate more often and help prevent kidney problems.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use aspirin or any other NSAID medicine (including diflunisal, salsalate) unless your doctor says it is okay.
• Some medicines can affect how meloxicam works. Tell your doctor if you are also using any of the following:
  • Amiodarone, cholestyramine, cyclosporine, digoxin, fluconazole, lithium, methotrexate, pemetrexed, phenytoin, sulphaphenazole
  • Blood pressure medicine
  • Blood thinner (including warfarin)
  • Diuretic (water pill)
  • Medicine to treat depression
  • Steroid medicine

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy unless your doctor tells you it is okay.
• Tell your doctor if you have kidney disease, liver disease, heart disease, heart failure, asthma, bleeding problems, high blood pressure, any heart or blood vessel problems, phenylketonuria, a recent heart attack, or a history of ulcers or other stomach problems. Tell your doctor if you smoke or drink alcohol regularly.
• This medicine may cause the following problems:
  • Increased risk of blood clots, heart attack, stroke, or heart failure
  • Bleeding problems, including stomach or bowel bleeding or ulcer
  • Liver problems
  • High blood pressure
  • Kidney problems
  • Serious skin reactions
• This medicine may cause a delay in ovulation for women and may decrease sperm count in men, which can affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Change in how much or how often you urinate, painful urination
• Chest pain, trouble breathing, coughing up blood
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
• Rapid weight gain, swelling in your hands, ankles, or feet
• Severe stomach pain, vomiting blood or material that looks like coffee grounds, bloody or black, tarry stools
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Constipation
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088