Brolucizumab-dbll (broe-lue-SIZ-ue-mab - dbll)

Treats neovascular (wet) age-related macular degeneration and diabetic macular edema.

Brand Name(s):

Beovu

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• An eye doctor (ophthalmologist) will give you this medicine as a shot into the eye.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for at least 1 month after the last dose.
• Do not breastfeed during treatment and for at least 1 month after the last dose.
• Tell your doctor if you have glaucoma, other eye problems, or a history of blood clots, heart attack, or stroke.
• This medicine may cause the following problems:
  • Eye problems, including a detached retina, endophthalmitis (swelling of the inner eye), retinal artery blockage or swelling, increased pressure inside your eye
  • Increased risk of blood clots, heart attack, or stroke
• This medicine may cause temporary blurred vision. Do not drive or do anything else that could be dangerous until you can see clearly.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bleeding in your eye
• Blurred vision, seeing floating spots, sensitivity to light
• Chest pain that may spread, trouble breathing, nausea, unusual sweating, faintness
• Eye pain, swelling, redness, or itching of your eyes or eyelids
• Irritated, dry, or watery eyes, a feeling that something is in your eyes
• Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
• Sudden or severe headache, problems with vision, speech, or walking

If you notice these less serious side effects, talk with your doctor:

• Floaters (seeing dark spots or lines in your field of vision), increased tearing

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088