Perflutren lipid microsphere (By injection)

Perflutren Lipid Microsphere (per-FLOO-tren LIP-id MYE-kroe-sfeer)

Used during an echocardiogram to help show the inside of your heart.

Brand Name(s):

Definity, Definity RT

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to perflutren lipid microsphere or polyethylene glycol.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • Your doctor may have special instructions for you in preparation for your test. If you do not understand the instructions you receive or if you have not received such instructions, check with your doctor in advance.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, lung disease, heart failure, heart rhythm problems, sickle cell disease, or a history of heart attack.
  • This medicine may cause serious heart or lung problems.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, trouble breathing
  • Fast, slow, pounding, or uneven heartbeat
  • Lightheadedness, dizziness, or fainting
  • Lower back or side pain
  • Seizures

If you notice these less serious side effects, talk with your doctor:

  • Headache, nausea
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/6/2024

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