Diflorasone (On the skin)

Diflorasone (dye-FLOR-a-sone)

Relieves pain, itching, and swelling caused by skin diseases. This medicine is a corticosteroid.

Brand Name(s):

Apexicon E, Psorcon

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to diflorasone diacetate.

How to Use This Medicine:

Cream, Ointment

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
  • Wash your hands with soap and water before and after you use this medicine.
  • Apply a thin layer of the medicine to the affected area. Rub it in gently.
  • Do not cover the treated area with a bandage unless directed by your doctor.
  • This medicine is not for long-term use.
  • Do not bandage, cover, or wrap the treated area unless your doctor tells you to. If this medicine is used on the diaper area of your child, avoid using tight-fitting diapers or plastic plants.
  • Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not put cosmetics or skin care products on the treated skin.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have cataracts, glaucoma, or any infection.
  • This medicine may cause eye or vision problems.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Do not use this medicine to treat a skin problem your doctor has not examined.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or vision changes
  • Color changes on the skin, dark freckles, easy bruising, muscle weakness
  • Gaining weight around your neck, upper back, breast, face, or waist
  • Swelling, redness, warmth, pus, or oozing

If you notice these less serious side effects, talk with your doctor:

  • Redness, itching, or swelling where the medicine is applied

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/27/2024

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