Anti-inhibitor coagulant complex (By injection)

Anti-Inhibitor Coagulant Complex (AN-tee in-HIB-i-ter co-AG-yoo-lant kom-plex)

Treats, controls, prevents, and decreases the frequency of bleeding episodes, and prevents bleeding during surgery in patients with hemophilia A and B.

Brand Name(s):

Feiba, Feiba NF

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to anti-inhibitor coagulant complex, or if you have a recent heart attack, bleeding problems caused by coagulation factor VIII or coagulation factor IX deficiencies, or disseminated intravascular coagulation (DIC).

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use aminocaproic acid and tranexamic acid within 6 to 12 hours after receiving this medicine.
  • Some medicines can affect how anti-inhibitor coagulant complex works. Tell your doctor if you are also using coagulation factor VIIa and emicizumab.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, blood clots, heart attack, injury, or stroke.
  • This medicine may increase your risk for blood clots.
  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses (including Creutzfeldt-Jakob disease) to people who have received them, although the risk is low. Human donors and donated blood are both tested for viruses to keep the transmission risk low. Talk with your doctor if you have concerns about this risk.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blood in the urine or stools, fever, chills
  • Chest pain, trouble breathing, or coughing up blood
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Sudden or severe headache, problems with vision, speech, or walking
  • Swelling of the face, around the eyes, or mouth

If you notice these less serious side effects, talk with your doctor:

  • Back pain
  • Headache
  • Tiredness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/6/2024

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