Morton neuroma

Definition

Morton neuroma is an injury to the nerve between the toes that causes thickening and pain. It commonly affects the nerve that travels between the 3rd and 4th toes.

Alternative Names

Morton neuralgia; Morton toe syndrome; Morton entrapment; Metatarsal neuralgia; Plantar neuralgia; Intermetatarsal neuralgia; Interdigital neuroma; Interdigital plantar neuroma; Forefoot neuroma; Morton's neuroma

Causes

The exact cause is unknown. Health care providers believe the following may play a role in the development of this condition:

Morton neuroma is more common in women than in men.

Symptoms

Symptoms may include:

In rare cases, nerve pain occurs in the space between the 2nd and 3rd toes. This is not a common form of Morton neuroma, but symptoms and treatment are similar.

Exams and Tests

Your provider can usually diagnose this problem by examining your foot. Squeezing your forefoot or toes together bring on the symptoms.

A foot x-ray may be done to rule out bone problems. MRI or ultrasound can successfully diagnose the condition.

Nerve testing (electromyography) cannot diagnose Morton neuroma. But it may be used to check for conditions that cause similar symptoms.

Blood tests may be done to check for inflammation-related conditions, including certain forms of arthritis.

Treatment

Nonsurgical treatment is tried first. Your provider may recommend any of the following:

Anti-inflammatories and painkillers are not recommended for long-term treatment.

In some cases, surgery is needed to remove the thickened tissue and inflamed nerve. This helps relieve pain and improve foot function. Numbness after surgery is permanent.

Outlook (Prognosis)

Nonsurgical treatment does not always improve symptoms. Surgery to remove the thickened tissue is successful in most cases.

Possible Complications

Complications may include:

When to Contact a Medical Professional

Contact your provider if you have constant pain or tingling in your foot or toe area.

Prevention

Avoid ill-fitting shoes. Wear shoes with a wide toe box or lower heels.

References

McGee DL. Podiatric procedures. In: Roberts JR, Custalow CB, Thomsen TW, eds. Roberts & Hedges' Clinical Procedures in Emergency Medicine and Acute Care. 7th ed. Philadelphia, PA: Elsevier; 2019:chap 51.

Shi GG. Morton's neuroma. In: Frontera WR, Silver JK, Rizzo TD Jr, eds. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 4th ed. Philadelphia, PA: Elsevier; 2019:chap 91.


Review Date: 4/24/2023
Reviewed By: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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