Mercury poisoning


Definition

This article discusses poisoning from mercury.

This article is for information only. DO NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.

Poisonous Ingredient

There are three different forms of mercury that cause health problems. They are:

Where Found

Elemental mercury can be found in:

Inorganic mercury can be found in:

Organic mercury can be found in:

There may be other sources of these forms of mercury.

Symptoms

ELEMENTAL MERCURY

Elemental mercury is usually harmless if it is touched or swallowed. It is so thick and slippery that it usually falls off the skin or leaves the stomach and intestines without being absorbed.

A lot of damage can occur, though, if elemental mercury gets into the air in the form of small droplets that are breathed into the lungs. This often occurs by mistake when people try to vacuum up mercury that has spilled onto the ground.

Breathing in enough elemental mercury will cause symptoms right away. These are called acute symptoms. Long-term symptoms will occur if small amounts are inhaled over time. These are called chronic symptoms. Chronic symptoms may include:

Depending on how much mercury is inhaled, permanent lung damage and death may occur. Long-term brain damage from inhaled elemental mercury can also occur.

There have been cases of mercury being injected under the skin, which can cause fever and rash. Infection may develop, requiring surgical drainage and removal of the mercury.

INORGANIC MERCURY

Unlike elemental mercury, inorganic mercury is usually poisonous when swallowed. Depending on how much is swallowed, symptoms may include:

If inorganic mercury enters your bloodstream, it can attack the kidneys and brain. Permanent kidney damage and kidney failure may occur. A large amount in the bloodstream may cause massive blood and fluid loss from diarrhea and kidney failure, leading to death.

ORGANIC MERCURY

Organic mercury can cause sickness if it is breathed in, eaten, or placed on the skin over long periods of time. Usually, organic mercury causes problems over years or decades, not right away. This means that being exposed to small amounts of organic mercury every day for years will likely cause symptoms to appear later. A single large exposure, however, can also cause problems.

Long-term exposure will likely cause symptoms in the nervous system, including:

Being exposed to large amounts of the organic mercury called methylmercury while pregnant may cause permanent brain damage in the baby. Most health care providers recommend eating less fish, especially high-mercury fish such as swordfish, while pregnant, and limiting the consumption of such fish by small children as well. Women should talk to their provider about what they should and should not eat while pregnant.

Before Calling Emergency

Have this information ready:

Do not delay calling for help if you do not know the above information.

Poison Control

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

What to Expect at the Emergency Room

General treatment for mercury exposure includes the steps just below. Treatment for exposure to different forms of mercury are given after this general information.

The person should be moved away from the source of exposure.

Your health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure.

Tests that may be done include:

Treatment may include:

The type of exposure will determine what other tests and treatments are needed.

ELEMENTAL MERCURY

Inhaled elemental mercury poisoning may be difficult to treat. The person may receive:

INORGANIC MERCURY

For inorganic mercury poisoning, treatment often begins with supportive care. The person may receive:

ORGANIC MERCURY

Treatment for exposure to organic mercury usually consists of medicines called chelators. These remove mercury from the blood and move it away from the brain and kidneys. Often, these medicines will have to be used for weeks to months.

Outlook (Prognosis)

Breathing in a small amount of elemental mercury will cause very few, if any, long-term side effects. However, breathing in larger amounts can lead to a long hospital stay. Permanent lung damage is likely. There may be brain damage. Very large exposures will likely cause death.

A large overdose of inorganic mercury may cause massive blood and fluid loss, kidney failure, and likely death.

Chronic brain damage from organic mercury poisoning is difficult to treat. Some people never recover, but there has been some success in people who receive chelation treatment.

References

Mahajan PV. Heavy metal intoxication. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 738.

Theobald JL, Mycyk MB. Iron and heavy metals. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 146.

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