Surgical excision is the removal of tissue. A sharp knife (scalpel) is typically used for skin tissue removal. For deeper tissue inside the body, specialized instruments are used, such as staplers, electrocautery devices, or ultrasonic scalpels.
Olbricht S. Biopsy techniques and basic excisions. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 146.