Definition

Epstein pearls are whitish-yellow cysts. These form on the gums and roof of the mouth in a newborn baby.

Milia are a similar type of skin problem in babies.

Alternative Names

Gingival cysts of the newborn

Causes

Epstein pearls occur only in newborns and are very common. They are seen in about 4 out of 5 newborns.

Symptoms

The symptoms are whitish-yellow nodules that appear on the gums or the roof of the mouth. They sometimes look like emerging teeth.

Exams and Tests

An exam confirms that these are cysts and not natal teeth.

Treatment

No treatment is necessary. The condition is harmless.

Outlook (Prognosis)

Epstein pearls disappear within 1 to 2 weeks of birth.

When to Contact a Medical Professional

If you are concerned about Epstein pearls in your infant, talk to your health care provider during a routine well-baby checkup.

References

Khorsand K, Sidbury R. Common newborn dermatoses. In: Gleason CA, Sawyer T, eds. Avery's Diseases of the Newborn. 11th ed. Philadelphia, PA: Elsevier; 2024:chap 94.

Lalor L. Disorders of the mucous membranes. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 705.

Turner EG, Dean JA. Eruption of the teeth: local, systemic, and congenital factors that influence the process. In: Dean JA, ed. McDonald and Avery's Dentistry for the Child and Adolescent. 11th ed. St Louis, MO: Elsevier; 2022:chap 20.