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Fibrinólisis primaria o secundaria

Formación de coágul...Formación de coágulos sanguíneos
Coágulos sanguíneosCoágulos sanguíneos

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Fibrinólisis primaria; Fibrinólisis secundaria

Definición

La fibrinólisis es un proceso corporal normal que impide que los coágulos sanguíneos que ocurren en forma natural crezcan y causen problemas.

La fibrinólisis primaria se refiere a la descomposición normal de los coágulos.

La fibrinólisis secundaria es la descomposición de los coágulos sanguíneos debido a un trastorno de salud, un medicamento u otra causa. Esto puede provocar sangrado intenso.

Causas

Los coágulos de sangre se forman en una proteína llamada fibrina. La descomposición de la fibrina (fibrinólisis) puede deberse a:

Infecciones bacterianas
Cáncer
Ejercicio intenso
Oxigenación insuficiente a los tejidos

El médico puede darle medicamentos para ayudar a que los coágulos sanguíneos se descompongan más rápidamente. Esto se puede hacer si un coágulo de sangre provoca un ataque cardíaco u otro problema médico.

Referencias

Brummel-Ziedins K, Mann KG, Fredenburgh JC, Weitz JI. Molecular basis of blood coagulation. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 125.

Schafer AI. Disseminated intravascular coagulation and bleeding in liver failure. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 161.

Weitz JI. Hemostasis, thrombosis, fibrinolysis, and cardiovascular disease. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 95.

Programe una cita

Actualizado : 3/31/2024

Versión en inglés revisada por : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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