Tea has been cultivated for centuries, beginning in India and China. Today, tea is the most widely-consumed beverage in the world, second only to water. Hundreds of millions of people drink tea, and studies suggest that green tea (Camellia sinesis) in particular has many health benefits.

There are 3 main varieties of tea, green, black, and oolong. The difference is in how the teas are processed. Green tea is made from unfermented leaves and reportedly contains the highest concentration of powerful antioxidants called polyphenols. Antioxidants are substances that fight free radicals, damaging compounds in the body that change cells, damage DNA, and even cause cell death. Many scientists believe that free radicals contribute to the aging process, as well as the development of a number of health problems, including cancer and heart disease. Antioxidants, such as polyphenols in green tea, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.

In traditional Chinese and Indian medicine, practitioners used green tea as a stimulant, a diuretic (to help rid the body of excess fluid), an astringent (to control bleeding and help heal wounds), and to improve heart health. Other traditional uses of green tea include treating gas, regulating body temperature and blood sugar, promoting digestion, and improving mental processes.

Green tea has been extensively studied in people, animals, and laboratory experiments. Results from these studies suggest that green tea may help treat the following health conditions:

Atherosclerosis

Population-based studies indicate that the antioxidant properties of green tea may help prevent atherosclerosis, particularly coronary artery disease. Population-based studies are studies that follow large groups of people over time or studies that compare groups of people living in different cultures or with different diets.

Researchers believe green tea reduces the risk of heart disease by lowering cholesterol and triglyceride levels. Studies show that black tea has similar effects. In fact, researchers estimate that the rate of heart attack decreases by 11% with consumption of 3 cups of tea per day.

High cholesterol

Research shows that green tea lowers total cholesterol and raises HDL (good) cholesterol in both animals and people. One population-based study found that men who drink green tea are more likely to have lower total cholesterol than those who do not drink green tea.

Results from one animal study suggest that polyphenols in green tea may block cholesterol from being absorbed in the intestine and also help the body get rid of cholesterol. In another small study of male smokers, researchers found that green tea significantly reduced blood levels of harmful LDL (bad) cholesterol.

Cancer

Several population-based studies suggest that both green and black teas help protect against cancer. For example, cancer rates tend to be low in countries such as Japan where people regularly consume green tea. However, it is not possible to know for sure from these studies whether green tea actually prevents cancer in people.

Early clinical studies suggest that the polyphenols in tea, especially green tea, may play an important role in the prevention of cancer. Researchers also believe that polyphenols help kill cancerous cells and stop them from growing.

Bladder cancer. In one study that compared people with and without bladder cancer, researchers found that women who drank black tea and powdered green tea were less likely to develop bladder cancer. A follow-up clinical study by the same group of researchers revealed that people with bladder cancer, particularly men, who drank green tea had a better 5-year survival rate than those who did not drink green tea. People with cancer should consult with their doctor before adding tea to their regimen.

Breast cancer. Studies in animals and test tubes suggest that polyphenols in green tea inhibit the growth of breast cancer cells. In one study of 472 women with various stages of breast cancer, researchers found that women who drank the most green tea had the least spread of cancer. It was especially true in premenopausal women in the early stages of breast cancer. They also found that women with early stages of the disease who drank at least 5 cups of tea daily before being diagnosed with cancer were less likely to experience a recurrence after they finished treatment. However, women with late stages of breast cancer had little or no improvement from drinking green tea.

There is no clear evidence one way or the other about green tea and breast cancer prevention. In one very large study, researchers found that drinking tea, green or any other type, was not associated with a reduced risk of breast cancer. However, when the researchers broke down the sample by age, they found that women under the age of 50 who consumed 3 or more cups of tea per day were 37% less likely to develop breast cancer compared to women who did not drink tea.

Ovarian cancer. In a study done with ovarian cancer patients in China, researchers found that women who drank at least one cup of green tea per day lived longer with the disease than those who did not drink green tea. In fact, those who drank the most tea, lived the longest. But other studies found no beneficial effects.

Colorectal cancer. Studies on the effects of green tea on colon or rectal cancer have showed conflicting results. Some studies show decreased risk in those who drink the tea, while others show increased risk. In one study, women who drank 5 or more cups of green tea per day had a lower risk of colorectal cancer compared to non-tea-drinkers. However, there was no protective effect for men. Other studies show that drinking tea regularly may reduce the risk of colorectal cancer in women. More research is needed before researchers can recommend green tea for the prevention of colorectal cancer.

Esophageal cancer. Studies in laboratory animals have found that green tea polyphenols inhibit the growth of esophageal cancer cells. However, studies in people have produced conflicting findings. For example, one large-scale population-based study found that green tea offered protection against the development of esophageal cancer, particularly among women. Another population-based study found just the opposite, green tea consumption was associated with an increased risk of esophageal cancer. In fact, the stronger and hotter the tea, the greater the risk. Given these conflicting results, more research is needed before scientists can recommend green tea for the prevention of esophageal cancer.

Lung cancer. While green tea polyphenols have been shown to inhibit the growth of human lung cancer cells in test tubes, few clinical studies have looked at the link between drinking green tea and lung cancer in people, and the studies that have been done show conflicting results. One population-based study found that Okinawan tea, similar to green tea but partially fermented, was associated with lower lung cancer risk, particularly among women. But a second study found that green tea and black tea increased the risk of lung cancer. More studies are needed before researchers can draw any conclusions about green tea and lung cancer. Green tea should not be used by patients on bortezomib therapy.

Pancreatic cancer. In one large-scale clinical study researchers compared green tea drinkers with nondrinkers and found that those who drank the most tea were less likely to develop pancreatic cancer. This was particularly true for women, those who drank the most green tea were half as likely to develop pancreatic cancer as those who drank less tea. Men who drank the most tea were 37% less likely to develop pancreatic cancer.

However, it is not clear from this population-based study whether green tea is solely responsible for lowering pancreatic cancer risk. More studies are needed before researchers can recommend green tea for the prevention of pancreatic cancer.

Prostate cancer. Laboratory studies have found that green tea extracts prevent the growth of prostate cancer cells in test tubes. A large clinical study in Southeast China found that the risk of prostate cancer went down with increasing frequency, duration, and quantity of green tea consumption. However, both green and black tea extracts also stimulated genes that cause cells to be less sensitive to chemotherapy drugs. People who are undergoing chemotherapy should ask their doctors before drinking green or black tea, or taking tea supplements.

Skin cancer. The main polyphenol in green tea is epigallocatechin gallate (EGCG). Scientific studies suggest that EGCG and green tea polyphenols have anti-inflammatory and anticancer properties that may help prevent the development and growth of skin tumors.

Stomach cancer. Laboratory studies have found that green tea polyphenols inhibit the growth of stomach cancer cells in test tubes, however, studies in people have been less conclusive. In two studies that compared green tea drinkers with nondrinkers, researchers found that people who drank tea were about half as likely to develop stomach cancer and stomach inflammation as those who did not drink green tea. However, a clinical study with more than 26,000 men and women in Japan found no association between green tea and stomach cancer risk. Some studies even suggest that green tea may increase the risk of stomach cancer.

More studies are underway to see whether green tea helps reduce the risk of stomach cancer.

Inflammatory Bowel Disease (IBD)

Green tea may help reduce inflammation associated with Crohn disease and ulcerative colitis, the two types of IBD. If green tea proves to help prevent colon cancer, it would also help those with IBD because they are at higher risk for colon cancer.

Diabetes

Green tea has been used traditionally to control blood sugar levels. Animal studies suggest that green tea may help prevent the development of type 1 diabetes and slow the progression once it has developed. In people with type 1 diabetes, their bodies make little or no insulin, which helps convert glucose or sugar into energy. Green tea may help regulate glucose in the body. Research also suggests that regular consumption of green tea may help manage type 2 diabetes.

Liver disease

Population-based studies have shown that men who drink more than 10 cups of green tea per day are less likely to develop liver problems. Green tea also seems to protect the liver from the damaging effects of toxic substances such as alcohol. Animal studies have shown that green tea helps protect against liver tumors in mice.

Results from several animal and human studies suggest that plant chemicals in green tea called catechins, may help treat viral hepatitis, an inflammation of the liver. In these studies, catechin was used by itself in very high amounts. It is not clear whether green tea, which has a lower concentration of catechins, would have the same benefits. It is important to note that 10 cups of green tea a day could cause problems due to high levels of caffeine. Ask your doctor about the best way to include green tea in your treatment.

Weight loss

Clinical studies suggest that green tea extract may boost metabolism and help burn fat. One study found that the combination of green tea and caffeine improved weight loss and maintenance in people who were overweight and moderately obese. However, other studies show no benefit.

Other uses

Preliminary studies suggest that drinking green tea can help prevent dental cavities. More research is needed. Green tea may also be useful in inflammatory diseases, such as arthritis. Research suggests that green tea may help arthritis by reducing inflammation and slowing the breakdown of cartilage. Chemicals in green tea may help treat genital warts, treat dermatologic conditions, and prevent symptoms of colds and flu. Green tea may play a role in preventing Parkinson disease, cognitive decline, and osteoporosis. Studies also show that drinking green tea is associated with reduced risk of dying from any cause.

Green, black, and oolong tea are all derived from the leaves of the Camellia sinensis plant. Originally cultivated in East Asia, this plant grows as large as a shrub or tree. Today, Camellia sinensis grows throughout Asia and parts of the Middle East and Africa.

People in Asian countries more commonly consume green and oolong tea while black tea is most popular in the United States. Green tea is prepared from unfermented leaves, the leaves of oolong tea are partially fermented, and black tea is fully fermented. The more the leaves are fermented, the lower the polyphenol content and the higher the caffeine content. Green tea has the highest polyphenol content while black tea has roughly 2 to 3 times the caffeine content of green tea.

Researchers think the health properties of green tea are mostly due to polyphenols, chemicals with potent antioxidant potential. In fact, the antioxidant effects of polyphenols seem to be greater than vitamin C. The polyphenols in green tea also give it a somewhat bitter flavor.

Polyphenols contained in teas are classified as catechins. Green tea contains six primary catechin compounds: catechin, gallaogatechin, epicatechin, epigallocatechin, epicatechin gallate, and apigallocatechin gallate (also known as EGCG). EGCG is the most studied polyphenol component in green tea and the most active.

Green tea also contains alkaloids including caffeine, theobromine, and theophylline. They provide green tea's stimulant effects. L-theanine, an amino acid compound found in green tea, has been studied for its calming effects on the nervous system.

Most green tea dietary supplements are sold as dried leaf tea in capsule form. Look for standardized extracts of green tea. There are also liquid extracts made from the leaves and leaf buds. The average cup of green tea contains 50 to 150 mg polyphenols (antioxidants). Decaffeinated green tea products contain concentrated polyphenols. Caffeine-free supplements are available.

Pediatric

Green tea has not been studied in children, so it is not recommended for pediatric use.

Adult

Depending on the brand, 2 to 3 cups of green tea per day (for a total of 240 to 320 mg polyphenols) or 100 to 750 mg per day of standardized green tea extract is recommended. Caffeine-free products are available and recommended.

The use of herbs is a time-honored approach to strengthening the body and treating disease. However, herbs contain active substances that can trigger side effects and interact with other herbs, supplements, or medications. For these reasons, people should take herbs with care, under the supervision of a practitioner knowledgeable in the field of botanical medicine.

People with heart problems or high blood pressure, kidney problems, liver problems, stomach ulcers, and psychological disorders, particularly anxiety, should not take green tea. Pregnant and breastfeeding women should also avoid green tea.

People with anemia, diabetes, glaucoma, or osteoporosis should ask their health care provider before drinking green tea or taking an extract.

People who drink large amounts of caffeine, including caffeine from green tea, for long periods of time may experience irritability, insomnia, heart palpitations, and dizziness. Caffeine overdose can cause nausea, vomiting, diarrhea, headaches, and loss of appetite. If you are drinking a lot of tea and start to vomit or have abdominal spasms, you may have caffeine poisoning. If your symptoms are severe, lower your caffeine intake and see your health care provider.

If you are being treated with any of the following medications, you should not drink green tea or take green tea extract without first talking to your health care provider:

Adenosine. Green tea may inhibit the actions of adenosine, a medication given in the hospital for an irregular and usually unstable heart rhythm.

Beta-lactam. Green tea may increase the effectiveness of beta-lactam antibiotics by making bacteria less resistant to treatment.

Benzodiazepines. Caffeine, including caffeine from green tea, may reduce the sedative effects of these medications commonly used to treat anxiety, such as diazepam (Valium) and lorazepam (Ativan).

Beta-blockers, Propranolol, and Metoprolol. Caffeine, including caffeine from green tea, may increase blood pressure in people taking propranolol (Inderal) and metoprolol (Lopressor, Toprol XL). These medications are used to treat high blood pressure and heart disease.

Blood-Thinning Medications. People who take warfarin (Coudamin) should not drink green tea. Since green tea contains vitamin K, it can make this medication ineffective. Other compounds in green tea may slow blood clotting and therefore increase the blood-thinning effect of these medications. You should not mix green tea and aspirin because they both prevent blood from clotting. Using the two together may increase your risk of bleeding. If you are taking medications that promote blood thinning, discuss green tea consumption with your physician.

Chemotherapy. The combination of green tea and chemotherapy medications, specifically doxorubicin and tamoxifen, increased the effectiveness of these medications in laboratory tests. However, the same results have not been found in studies on people. On the other hand, there have been reports of both green and black tea extracts affecting a gene in prostate cancer cells that may make them less sensitive to chemotherapy drugs. For that reason, people should talk to their doctors before drinking black and green tea or taking tea extracts while undergoing chemotherapy.

Clozapine (Clozaril). The effects of the clozapine may be reduced if taken within 40 minutes after drinking green tea.

Ephedrine. When taken with ephedrine, green tea may cause agitation, tremors, insomnia, and weight loss.

Lithium. Green tea has been shown to reduce blood levels of lithium, a medication used to treat bipolar disorder. That can make lithium less effective.

Monoamine Oxidase Inhibitors (MAOIs). Green tea may cause a severe increase in blood pressure, called a "hypertensive crisis," when taken together with these drugs used to treat depression. Examples of MAOIs include:

• Isocarboxazid (Marplan)
• Moclobemide (Manerix)
• Phenelzine (Nardil)
• Tranylcypromine (Parnate)

Birth control pills. Oral contraceptives can prolong the amount of time caffeine stays in the body, which may increase its stimulating effects.

Phenylpropanolamine. A combination of caffeine, including caffeine from green tea, and phenylpropanolamine, used in many over-the-counter and prescription cough and cold medications and weight loss products, may cause mania and a severe increase in blood pressure. The FDA issued a public health advisory in November 2000 to warn people of the risk of bleeding in the brain from use of this medication and urged all manufacturers of this drug to remove it from the market. Most drugs that contained phenylpropanolamine have been reformulated without it.

Quinolone antibiotics. Green tea may make these medications more effective and also increase the risk of side effects. These medications include:

• Ciprofloxacin (Cipro)
• Enoxacin (Penetrex)
• Grepafloxacin (Raxar)
• Norfloxacin (Chibroxin, Noroxin)
• Sparfloxacin (Zagam)
• Trovafloxacin (Trovan)

Other medications. Green tea, especially caffeinated green tea, may interact with a number for medications, including:

• Acetaminophen (Tylenol)
• Carbamazepine (Tegretol)
• Dipyridamole (Persatine)
• Estrogen
• Fluvoxamine (Luvox)
• Methotrexate
• Mexiletine (Mexitil)
• Phenobarbital
• Theophylline
• Verapamil (Bosoptin, Calan, Covera- HS, Verelan, Verelan PM)

To be safe, check with your health care provider before drinking or taking green tea if you also take other medications.

Baladia E, Basulto J, Manera M, Martinez R, Calbet D. Effect of green tea or green tea extract consumption on body weight and body composition: systematic review and meta-analysis. Nutr Hosp. 2014; 2993):479-90.

Belza A, Toubro S, Astrup A. The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake. Eur J Clin Nutr. 2007; [Epub ahead of print].

Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A. Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res. 2006;66(2):1234-40.

Borrelli F, Capasso R, Russo A, Ernst E. Systematic review: green tea and gastrointestinal cancer risk. Aliment Pharmacol Ther. Mar 1, 2004;19(5):497-510.

Boschmann M, Thielecke F. The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study. J Am Coll Nutr. 2007;26(4):389S-95S.

Brown AL, Lane J, Holyoak C, Nicol B, Mayes AE, Dadd T. Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. Br J Nutr. 2011 Jun 7:1-10. [Epub ahead of print]

Cooper R, Morre DJ, Morre DM. Medicinal benefits of green tea: Part I. Review of noncancer health benefits. J Altern Complement Med. 2005;11(3):521-8.

Diepvens K, Westerterp KR, Westerterp-Plantenga MS. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin and green tea. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R77-85.

Fritz H, Seely D, Kennedy DA, Fernandes R, Cooley K, Fergusson D. Green tea and lung cancer: a systemic review. Integr Cancer Ther. 2013;12(1):7-24.

Fujita H, Yamagami T. Antihypercholesterolemic effect of Chinese black tea extract in human subjects with borderline hypercholesterolemia. Nutr Res. 2008;28(7):450-6.

Fukino Y, Ikeda A, Maruyama K, Aoki N, Okubo T, Iso H. Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. Eur J Clin Nutr. 2007; [Epub ahead of print].

Gross G, Meyer KG, Pres H, Thielert C, Tawfik H, Mescheder A. A randomized, double-blind, four-arm parallel-group, placebo-controlled Phase II/III study to investigate the clinical efficacy of two galenic formulations of Polyphenon(R) E in the treatment of external genital warts. J Eur Acad Dermatol Venereol. 2007;21(10):1404-12.

Hartley L, Flowers N, Holmes J, et al. Green and black tea for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2013;6(1):CD009934.

Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. [review]. Am J Health Syst Pharm. 2000 Jul 1;57(13):1221-7.

Hsu CH, Liao YL, Lin SC, Tsai TH, Huang CJ, Chou P. Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. Altern Med Rev. 2011 Jun;16(2):157-63.

Inoue M, Tajima K, Mizutani M, et al. Regular consumption of green tea and the risk of breast cancer recurrence: follow-up study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), Japan. Cancer Lett. 2001;167(2):175-82.

Jian L, Xie LP, Lee AH, Binns CW. Protective effect of green tea against prostate cancer: a case-control study in southeast China. Int J Cancer Jan 1, 2004;108(1):130-5.

Jiao H, Hu G, Gu D, Ni X. Having a promising efficacy on type II diabetes, it's definitely a green tea time. Curr Med Chem. 2015;22(1):70-9.

Jin X, Zheng RH, Li YM. Green tea consumption and liver disease: a systematic review. Liver Int. 2008;28(7):990-6.

Katiyar SK, Ahmad N, Mukhtar H. Green tea and skin. Arch Dermatol. 2000;136(8):989-94.

Kato A, Minoshima Y, Yamamoto J, Adachi I, Watson AA, Nash RJ. Protective effects of dietary chamomile tea on diabetic complications. J Agric Food Chem. 2008;56(17):8206-11.

Khalesi S, Sun J, Buys N, et al. Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials. Eur J Nutr. 2014;53(6):1299-311.

Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007;74(1):39-45.

Koo SI, Noh SK. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. J Nutr Biochem. 2007;18(3):179-83.

Kovacs EM, Lejeune MP, Nijs I, Westerterp-Plantenga MS. Effects of green tea on weight maintenance after body-weight loss. Br J Nutr. Mar 1, 2004;91(3):431-7.

Kuriyama S, Shimazu T, Ohmori K, Kikuchi N, Nakaya N, Nishino Y, Tsubono Y, Tsuji I. Green tea consumption and mortality due to cardiovascular disease, cancer and all causes in Japan: the Ohsaki study. JAMA. 2006;296(10):1255-65.

Lee W, Min WK, Chun S, Lee YW, Park H, Lee do H, Lee YK, Son JE. Long-term effects of green tea ingestion on atherosclerotic biological markers in smokers. Clin Biochem. Jan 1, 2005;38(1):84-87.

Liu K, Zhou R, Wang B, et al. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials. Am J Clin Nutr. 2013;98(2):340-8.

Low Dog T, Riley D, Carter T. Traditional and alternative therapies for breast cancer. Alt Ther. 2001;7(3):36-47.

McKenna DJ, Hughes K, Jones K. Green tea monograph. Alt Ther. 2000;6(3):61-84.

Miura Y, Chiba T, Tomita I, et al. Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice. J Nutr. 2001;131(1):27-32.

Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007;15(6):1473-83.

Narotzki B, Reznick AZ, Aizenbud D, Levy Y. Green tea: a promising natural product in oral health. Arch Oral Biol. 2012; 57(5):429-35.

Noguchi-Shinohara M, Yuki S, Dohmoto C, et al. Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline. PLoS One. 2014; 9(5):e96013.

Pazyar N, Feily A, Kazerouni A. Green tea in dermatology. Skinmed. 2012;10(6):352-5.

Peters U, Poole C, Arab L. Does tea affect cardiovascular disease? A meta-analysis. Am J Epidemiol. 2001;154(6):495-503.

Pianetti S, Guo S, Kavanagh KT, Sonenshein GE. Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res. 2002;62(3):652-5.

Rakel. Integrative Medicine. 3rd ed. Philadelphia, PA: Elsevier Saunders; 2012.

Rowe CA, Nantz MP, Bukowski JF, Percival SS. Specific formulation of Camellia sinensis prevents cold and flu symptoms and enhances gammadelta T cell function: a randomized, double-blind, placebo-controlled study. J Am Coll Nutr. 2007;26(5):445-52.

Ryu OH, Lee J, Lee KW, et al. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res Clin Pract. 2006;71(3):356-8.

Sano T, Sasako M. Green tea and gastric cancer. N Engl J Med. 2001;344(9):675-6.

Sasazuki S, Kodama H, Yoshimasu K et al. Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women. Ann Epidemiol. 2000;10:401-8.

Setiawan VW, Zhang ZF, Yu GP, et al. Protective effect of green tea on the risks of chronic gastritis and stomach cancer. Int J Cancer. 2001;92(4):600-4.

Shankar S, Ganapathy S, Hingorani SR, Srivastava RK. EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer. Front Biosci. 2008;13:440-52.

Steptoe A, Gibson EL, Vuonovirta R, Hamer M, Wardle J, Rycroft JA, Martin JF, Erusalimsky JD. The effects of chronic tea intake on platelet activation and inflammation: a double-blind placebo controlled trial. Atherosclerosis. 2007;193(2):277-82.

Suzuki Y, Tsubono Y, Nakaya N, Suzuki Y, Koizumi Y, Tsuji I. Green tea and the risk of breast cancer: pooled analysis of two prospective studies in Japan. Br J Cancer. Apr 5, 2004;90(7)1361-3.

Thatte U, Bagadey S, Dahanukar S. Modulation of programmed cell death by medicinal plants. [Review]. Cell Mol Biol. 2000;46(1):199-214.

Thavanesan N. The putative effects of green tea on body fat: an evaluation of the evidence and a review of the potential mechanisms. Br J Nutr. 2011 Aug 3:1-13. [Epub ahead of print]

Trudel D, Labbe DP, Bairati I, Fradet V, Bazinet L, Tetu B. Green tea for ovarian cancer prevention and treatment: a systemic review of the in vitro, in vivo and epidemiological studies. Gynecol Oncol. 2012;126(3):491-8.

Tsubono Y, Nishino Y, Komatsu S, et al. Green tea and the risk of gastric cancer in Japan. N Engl J Med. 2001;344(9):632-6.

Vinson JA, Teufel K, Wu N. Green and black teas inhibit atherosclerosis by lipid, antioxidant, and fibrinolytic mechanisms. J Agric Food Chem. 2004;52(11):3661-5.

Wargovich MJ, Woods C, Hollis DM, Zander ME. Herbals, cancer prevention and health. [Review]. J Nutr. 2001;131(11 Suppl):3034S-36S.

Westerterp-Plantenga MS, Lejeune MP, Kovacs EM. Body weight and weight maintenance in relation to habitual caffeine intake and green tea. Obes Res. Jul 2005;13(7):1195-204.

Wu AH, Butler LM. Green tea and breast cancer. Mol Nutr Food Res. 2011 Jun;55(6):921-30.

Yang G, Shu XO, Li H, Chow WH, Ji BT, Zhang X, Gao YT, Zheng W. Prospective cohort study of green tea consumption and colorectal cancer risk in women. Cancer Epidemiol Biomarkers Prev. 2007;16(6):1219-23.

Yang G, Zheng W, Xiang YB, Gao J, Li HL, Zhang X, Gao YT, Shu XO. Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health Study. Carcinogenesis. 2011 Sep 8. [Epub ahead of print]

Yuan JM. Cancer prevention by green tea: evidence from epidemiologic studies. Am J Clin Nutr. 2013; 98(6 Suppl):1676S-81S.

Yuan JM. Green tea and prevention of esophageal and lung cancers. Mol Nutr Food Res. 2011 Jun;55(6):886-904.

Zhang M, Lee AH, Binns CW, Xie X. Green tea consumption enhances survival of epithelial ovarian cancer. Int J Cancer. Nov 10, 2004;112(3):465-9.

Zheng J, Yang B, Huang T, Yu Y, Yang J, Li D. Green tea and black tea consumption and prostate cancer risk: an exploratory meta-analysis of observational studies. Nutr Cancer. 2011;63(5):663-72. Epub 2011 Jun 11.

Zheng XX, Xu YL, Li SH, Liu XX, Hui R, Huang XH. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. Am J Clin Nutr. 2011;94(2):601-10.

Zheng XX, Xu YL, Li SH, Hui R, Wu YJ, Huang XH. Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2013;97(4):750-62.

Zhou B, Yang L, Wang L, Shi Y, Zhu H, Tang N, Wang B. The association of tea consumption with ovarian cancer risk: a meta-analysis. Am J Obstet Gynecol. 2007;197(6):594.e1-6.